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More About This Title The Cancer Handbook 2e 2VST
English
The Cancer Handbook stands out from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. It is also important for laboratory scientists to appreciate the potential applications of their research and the practical issues involved in translating it to clinical practice.
For this second edition, all the sections have been fully revised and updated, with new chapters addressing important topics that have gained prominence in recent years. New editors and authors have brought additional expertise to the project. For example, in the section on the Molecular and Cellular Basis of Cancer, there are new chapters on stem cells, epigenetics, and microRNAs, as well as chapters on the links between cancer and development and inflammation. In the Treatment section, the emphasis is now on multidisciplinary team management of different cancers, plus there are new chapters on clinical trial design, RNA interference and rational drug design.
The page design and the quality of the diagrams has been improved, with all illustrations now in full colour. The glossary has been made more informative and easy to use.
English
Malcolm R. Alison is the editor of The Cancer Handbook, 2 Volume Set, 2nd Edition, published by Wiley.
English
1 Cell and Tissue Organization
2 Stem Cells and Tumorigenesis
3 Regulation of the Cell Cycle, Cell Cycle Checkpoints, and Cancer
4 Apoptosis
5 Genetic Susceptibility to Cancer
6 The Role of Epigenetic Alterations in Cancer
7 Genomic Instability and DNA Repair
8 Micro-RNAs as Oncogenes and Tumour Suppressors
9 Regulation of Translation in Malignant Transformation
10 Human DNA Tumour Viruses
11 RNA Tumour Viruses
12 Invasion and Metastasis
13 Angiogenesis
14 The Biology of Tumour Stroma
15 The Links between Inflammation and Cancer
16 Telomerase
17 Signalling by Steroid Receptors
18 Signalling by Cytokines
19 Signalling by Tyrosine Kinases
20 Signaling by Ras and Rho GTPases
21 Wnt Signal Transduction
22 Transforming Growth Factor-ß And Cancer
23 p53 Family Pathway in Cancer
24 The Retinoblastoma Tumour Suppressor
25 Development and Cancer- The HOX Gene Connection
Part II The Causation and Prevention of Cancer
26 Epidemiology in the Identification of Cancer Causes
27 Mechanisms of Chemical Carcinogenesis
28 The Formation of DNA Adducts
29 Physical Causes of Cancer
30 Non-genotoxic Causes of Cancer
31 Infectious Agents and Cancer
32 Short-Term Testing for Genotoxicity
33 Cancer Bioassays
34 Molecular Epidemiology of Cancer and the Use of Biomarkers
35 Dietary Genotoxins and Cancer
36 Tobacco Use and Cancer
37 Occupational Causes of Cancer
38 Intervention and Chemoprevention of Cancer - Treatment of Carcinogenesis
Part III Systematic Oncology
39 Introduction to the Diagnosis of Cancer
40 Skin
41 Oral Cavity and Major and Minor Salivary Glands
42 Respiratory System
43 Upper Gastrointestinal Tract
44 Lower Gastrointestinal Tract
45 Pancreas
46 Liver, Gallbladder, and Extrahepatic Bile Ducts
47 Endocrine Organs
48 Breast
49 Female Reproductive System
50 Urinary Tract
51 Male Genital Tract
52 Lymph Nodes
53 Blood and Bone Marrow: Myeloid Leukaemias and Related Neoplasms
54 Bones
55 Soft Tissues
56 Pleura and Peritoneum
57 Heart
58 Neuromuscular System
59 Eye and Ocular Adnexa
60 Ear
61 Unknown Primary
Part IV Pre-clinical models for Human Cancer
62 Advantages and Limitations of Models for Cancer and Malignant Cell Progression
63 Basic Tissue and Cell Culture in Cancer Research
64 Transgenic Technology in the Study of Oncogenes and Tumour-Suppressor Genes
65 Genetic Models: A Powerful Technology for the Study of Cancer
66 Gene Knockouts in Cancer Research
67 Human Tumours in Animal Hosts
68 Mathematical Models of Cancer Growth and Development
69 Models for Tumour Growth and Differentiation
70 Models for Tumour Cell-Stromal Cell Interactions
71 Models for Angiogenesis
72 Models for Tumour Cell Adhesion and Invasion
73 Models for Tumour Cell-Endothelial Cell Interactions
74 Models for Tumour Metastasis
75 Models for Drug Development and Drug Resistance
76 Models for Immunotherapy and Cancer Vaccines
77 Models for Gene Therapy
78 Models for Breast Cancers
79 Models for Prostate Cancer
80 Models for Genitourinary Cancer - Hereditary Renal Carcinogenesis
81 Mouse Models for Gastrointestinal Carcinomas
82 Models for Liver Cancer
83 Models for Lymphoma
84 Models for Human Leukaemias
85 Models for Sarcomas
86 Models for Skin Cancer
87 Models for CNS Malignancies
Part V The Treatment of Cancer
88 Conventional Chemotherapeutics
89 Rational Drug Design of Small Molecule Anticancer Agents: Preclinical Discovery
90 Rational Drug Design of Small Molecule Anticancer Agents: Early Clinical Development
91 Modern Approaches to Radiation Therapy
92 Gene and Viral Therapy
93 Cancer Vaccines
94 Antibody Therapy for Cancer
95 Anti-angiogenic and Anti-stromal Therapy
96 RNA Interference
97 Cancer Chemoprevention
98 Mechanisms and Management of Cancer Pain
99 Clinical Trial Design for Anticancer Therapies
100 Head and Neck Cancer
101 Melanoma
102 Antihormonal Therapy for Breast and Prostate Cancer
103 Collaborative Approach to Multidisciplinary Breast Cancer Care
104 Management of Haematological Malignancies
105 Multidisciplinary Team Management of Lung Cancer
106 Multidisciplinary Team Management of Gynaecological Cancers
107 Multidisciplinary Management of Genitourinary Malignancies
108 Multidisciplinary Team Management of Upper Gastrointestinal, Hepatic, Pancreatic, and Biliary Cancers
109 Multidisciplinary Team Management of Colorectal Cancer.
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"…a valuable addition to most medical school libraries and also to the collection of most graduate and oncologic training programs." (Doody's Health Services)
