Title Details

Immunopharmacology of Infectious Diseases: Vaccine Adjuvants & Modulators of Non Specific Resistance (Progress in Leukocyte Biology-PLKB V6)
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  • Wiley

More About This Title Immunopharmacology of Infectious Diseases: Vaccine Adjuvants & Modulators of Non Specific Resistance (Progress in Leukocyte Biology-PLKB V6)

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English

Presenting recent advances in worldwide research into the prophylaxis and therapy of infectious disease, this work offers a comprehensive analysis of structure-function aspects of vaccine adjuvant research. Its primary focus is on new data on host defense machanisms and the drugs that modulate them, including some compounds never before discussed in the medical literature. Included is a general overview of current adjuvant research, plus discussions covering potential targets of immunomodulatory drugs, physiological systems not previously believed to affect immune competence, vaccine adjuvants derived from bacterial products, and synthetic adjuvants and vaccine design approaches. Also offers extensive coverage of immunomodulators of non-specific resistance which includes a comparative analysis of several compounds, a paper on Chinese medicinal materials, and a review of immunomodulators in infectious models.
  • English

English

Partial table of contents:

POTENTIAL TARGETS OF IMMUNOMODULATORS.

An Overview of Host Defense Mechanisms (A. Allison).

Nutritional and Metabolic Factors in Host Responses to Infection (W. Beisel).

ADJUVANT ACTION OF MICROBIAL PRODUCTS.

Bacterial Endotoxins: Relation of Chemical Structure to Biological Activity (E. Rietschel et al.).

Natural and Synthetic Trehalose Diesters as Immunomodulators (E. Lederer et al.).

SYNTHETIC ADJUVANTS.

The Differential Adjuvant Activity of AL(OH)3 and Saponin (R. Bomford).

Vaccination by Synthetic Peptide-MDP Contructs (F. Audibert).

MODULATORS OF NON-SPECIFIC RESISTANCE.

Mechanisms of Immunostimulation by Pyrimidinones (D. Tracey & K. Richard).

The Immunomodulatory Properties of Chinese Medicinal Materials (K. Leung & H. Yeung).

Index

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