Title Details

Rob Clarke (1956-2004) was Senior Lecturer in Animal Physiology at Nottingham University and had extensive experience of teaching Physiology to a wide range of biomedical students.

Roger Linden is Professor of Craniofacial Biology and Head of the Academic Department of Physiology in the School of Biomedical Sciences at King's College London. He is qualified in both dental surgery and physiology and is involved in teaching and examining physiology and oral biology to medical, dental and biomedical students both in the UK and abroad.

1. Physiology and the genome.

2. Homeostasis and the physiology of proteins.

3. Body water compartments and the physiological fluids.

4. Cells, membranes and organelles.

5. Membrane transport proteins and ion channels.

6. Biological electricity.

7. Conduction of action potentials.

8. The autonomic nervous system.

9. Blood.

10. Inflammation and immunity.

11. Principles of diffusion and flow.

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Part 2: The cardiovascular system.

12. Introduction to the cardiovascular system.

13. The Heart.

14. The cardiac cycle.

15. Initiation of the heart beat and excitation-contraction coupling.

16. Control of cardiac output and Starling's law of the heart.

17. Blood vessels.

18. Control of blood pressure and blood volume.

19. The microcirculation, filtration and lymphatics.

20. Local control of blood flow and special ciruculations.

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Part 3: The respiratory system.

21. Introduction to the respiratory system.

22. Lung mechanics.

23. Transport of gases and the gas laws.

24. Carriage of oxygen and carbon dioxide by the blood.

25. Control of breathing.

26. Ventilation-perfusion matching and right to left shunts.

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Part 4: The renal system.

27. Introduction to the renal system.

28. Renal filtration.

29. Reabsorption and secretion and the proximal tubule.

30. The loop of Henle and distal nephrons.

31. Regulation of plasma osmolality and fluid volume.

32. Control of acid-base.

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Part 5: The gut and metabolism.

33. Gastrointestinal tract: overview and the mouth.

34. Oesophagus and stomach.

35. Small intestine.

36. The exocrine pancreas, liver and gallbladder.

37. Large intestine.

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Part 6: Endocrinology and reproduction.

38. Endocrine control.

39. Control of metabolic fuels.

40. The hypothalamus and the pituitary gland.

41. Thyroid hormones and metabolic rate.

42. Growth factors.

43. Somatic and skeletal growth.

44. Control of plasma calcium.

45. The adrenal glands and stress.

46. Endocrine control of reproduction.

47. Sexual differentiation and function.

48. Fertilization, pregnancy and parturition.

49. Lactation.

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Part 7: The musculoskeletal system.

50. Skeletal muscle and its contraction.

51. Neuromuscular junction and whole muscle contraction.

52. Motor units, recruitment and summation.

53. Cardiac and smooth muscle.

Part 8: The sensory and motor systems.

54. Introduction to sensory systems.

55. Sensory receptors.

56. Special senses (taste and smell).

57. Vision.

58. Hearing and balance.

59. Motor control and the cerebellum.

60. Proprioception and reflexes.

Appendix.

Index