Title Details

Part 1: Immunological Basis of the Allergic Response:.

A Short History of Allergological Diseases and Concepts;.

Concepts of Allergy and Hypersensitivity;.

T and B Lymphocytes and the Development of Allergic Reactions;.

Immunoglobulin Structure, Synthesis and Genetics;.

IgE and IgE Receptors;.

Regulation of IgE Synthesis;.

Antigen Processing and Presentation;.

Immunological Tolerance and T-Cell Anergy;.

Part 2: Inflammatory Cells and Mediators:.

Human Mast Cells and Basophils;.

Eosinophils and the Allergic Inflammatory Response;.

The Neutrophil;.

Platelets;.

Macrophages and Dendritic Cells in Allergic Reactions;.

Leucocyte Adhesion in Allergic Inflammation;.

Airway Epithelium in Asthma;.

Endothelial Cells in Allergy;.

Fibroblasts and Bronchial Asthma;.

Complement and Antigen-Antibody Complexes;.

Intrinsic Coagulation/Bradykinin-Forming Cascade;.

Cytokines (Interleukins);.

Role of IL-5, IL-3 and GM-CSF in the Pathophysiology of Asthma and Allergy;.

Chemokines;.

Lipid Mediators - Leukotrienes, Prostanoids and Platelet-Activating Factor;.

Part 3: Pharmacology:.

Histamine and Antihistamines;.

Vascular Permeability and Plasma Exudation;.

Neuropeptides;.

The Autonomic Nervous System in Asthma and Rhinitis;.

Neuropharmacology;.

Endothelin and Nitric Oxide;.

Theophylline and Isoenzyme-Selective Phosphodiesterase Inhibitors;.

Adrenergic Agonists and Antagonistis;.

Nedocromil Sodium and Sodium Cromoglycate: Pharmacology and Putative Modes of Action;.

Cholinergic Antagonists;.

Potassium Channel Openers as Anti-Asthma Drugs;.

Glucocorticosteroids;.

Immunosuppressants (Drugs and Monoclonal Antibodies);.

Part 4: Physiology:.

Physiological Aspects of Airway, Pulmonary and Respiratory Muscle Function in Asthma;.

Bronchial Hyperresponsiveness;.

Exercise-Induced Asthma;.

Mucus and Mucociliary Clearance;.

New Approaches in Aerosol Drug Delivery for the Treatment of Asthma;.

Airway Smooth Muscle;.

Part 5: Cellular and Molecular Techniques in the Study of Allergic Disease:.

T-Cell Cloning;.

In Situ Hybridization;.

Immunocytochemistry;.

Polymerase Chain Reaction;.

Volume 2:.

Part 6: Allergens:.

Biochemistry of Allergens;.

Molecular Cloning of Allergens;.

Allergen Extracts and Standardization;.

Grass, Tree and Weed Pollens;.

Fungi and Actinomycetes as Allergens;.

Dust Mites and Asthma;.

Animal Allergens;.

Allergens in the Workplace;.

Allergens from Stinging Insects;.

Cockroach Allergens and their Role in Asthma;.

Chronomidae;.

Food Allergens;.

Latex Allergy;.

Part 7: Diagnostic Methods and the Assessment of Allergic Diseases:.

Principles and Interpretation of Laboratory Tests for Allergy;.

Skin Tests;.

Quantification of IgE both as Total Immunoglobulin and as Allergen-Specific Antibody;.

Part 8: Major Animal Models of Asthma and Hyperresponsiveness:.

Primate Models of Allergic Asthma;.

Sheep Models of Allergic Broncoconstriction;.

Murine Models of Allergy, Asthma and Hyperresponsiveness;.

The Allergic Response in Rats;.

The Rabbit as an Animal Model of Allergy, Asthma and Airway Hyperresponsiveness;.

The Sensitized Guinea Pig as a Model of Allergic Asthma;.

Canine Models of Asthma and Hyperresponsiveness;.

Part 9: Human Models of Allergic Inflammation (Late-Phase Reactions):.

Human Late Asthmatic Responses;.

Late-Phase Skin Reactions;.

Late-Phase Reactions in the Nose;.

Part 10: General Principles of the Allergic Response in Humans:.

Allergy and Helminthic Parasites: Are Atopics Protected Against Infection?.

Familial Inheritance of Asthma and Allergy;.

Genetics of Atopy;.

Genetics of Allergy and Asthma;.

Epidemiology of Atopy and Atopic Disease;.

Part 11: Allergen Injection Immunotherapy:.

Mechanisms;.

Indications for Specific Immunotherapy;.

Practical Immunotherapy;.

Part 12: The Practice of Allergology:.

Allergology as a Medical Specialty or Sub-Specialty;.

Principles and Practice of Diagnostic and Treatment of Allergic Disease;.

Part 13: Seasonal and Perennial Rhinitis:.

The Classification and Diagnosis of Rhinitis;.

Structure and Function of the Upper Airways;.

Seasonal and Perennial Allergic Rhinitis;.

Treatment and Management;.

Part 14: Asthma:.

Definition, Clinical Features, Investigations and Differential Diagnosis of Asthma;.

Post-Mortem Pathology in Asthma;.

Aetiology and Pathogenesis of Asthma;.

The T-Cell Hypothesis of Chroniic Asthma;.

Air Pollution and Allergic Disease;.

Pathology of Asthma;.

Treatment of Chronic Asthma in Adults;.

Delivery Systems;.

Childhood Asthma;.

Occupational Asthma;.

Part 13: Other Allergic Diseases:.

Extrinsic Allergic Alveolitis;.

Pulmonary Eosinophilia;.

Food Allergy;.

Anaphylaxis;.

Atopic Dermatitis;.

Urticaria and Angioedema;.

Contact Dermatitis;.

Otitis Media;.

Ocular Allergy;.

Drug Reactions;.

Insect-Sting Allergy;.

Part 16: Prevention of Allergic Disease and Future Trends:.

Prevention of Allergic Diseases and Sensitization;.

Prevention of Allergy in the Fetus and Newborn;.

New Treatment Drugs for Asthma.

Index