Title Details

Section I: Disorders of Water, Elecrolytes, and Acid-Base.

Introduction.

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Chapter 1.

Diseases of Water Metabolism.

Sumit Kumar and Tomas Berl.

Physiology of the Renal Diluting and Concentrating Mechanisms.

Control of Water Balance and Serum Sodium Concentration.

Approach to the Hyponatremic Patient.

Approach to the Hypernateremic Patient.

Chapter 2.

Disorders of Sodium Balance.

David H Ellison.

Normal Extracellular Fluid Volume Homeostatsis.

Mechanisms of Extracellular Fluid Volume Control.

Mechanisms of Sodium and Chloride Transport Along the Nephron.

Causes, Signs, and Symptoms of Extracellular Fluid Volume Expansion and Contraction.

Unifying Hypothesis of Renal Sodium Excretion.

Mechanisms of Extracellular Fluid Volume Expansion in Congestive Heart Failure.

Mechanisms of Extracellular Fluid Volume Expansion in Cirrhosis.

Mechanisms of Extracellular Fluid Volume Expansion in Nephrotic Syndrome.

Extracellular Fluid Volume Homeostasis in Chronic Renal Failure.

Chapter 3.

Disorders of Potassium Metabolism.

Fredrick V Osorio and Stuart L Linas.

Overview of Potassium Pysiology.

Hypokalemia: Diagnostic Approach.

Hypokalemia: Clinical Manifestations.

Hypokalemia: Treatment.

Hyperkalemia: Diagnostic Approach.

Hyperkalemia: Clinical Manifestations.

Myperkalemia: Treatment.

Chapter 4.

Divalent Cation Metabolism: Magnesium.

James T McCarthy and Rafiv Kumar.

Magnesium Distribution.

Intracellular Magnesium Metabolism.

Gastrointestinal Absorption of Magnesium.

Renal Handling of Magnesium.

Magnesium Depletion.

Chapter 5.

Divalent Cation Metabolism: Calcium.

James T McCarthy and Rajiv Kumar.

Calcium Distribution.

Intracellular Calcium Metabolism.

Vitamin D and Parathyriod Hormone Actions.

Gastrointestinal Absorption of Calcium.

Renal Handling of Calcium.

Disturbances of Serum Calcium.

Secondary Hyperparathyroidsm.

Calcium and Vitamin D Preparations.

Chapter 6.

Disorders of Acid-Base Balance.

Horacio J Androgue and Nicolaos E Madias.

Respiratory Acidosis.

Respiratory Alkalosis.

Metabolic Alkalosis.

Chapter 7.

Disorders of Phosphate Balance.

Moshe Levi and Mordicai Popovtzer.

Renal Tubular Phosphate Reabsorption.

Hypophosphatemia/Hyperphosphatemia.

Section II: Acute Renal Failure.

Introduction.

Chapter 8.

Acute renal Failure: Causes and Prognosis.

Fernando Liano.

Causes of Acute Renal Failure.

Epidemiology of Acute Renal Failure.

Hospital-Related Epidemiologic Data.

Prognosis.

Chapter 9.

Renal Histopatology, Urine Cytology, and Cytopathology of Acute Renal Failure Lorraine C. Racusen and Cynthia C Nast.

Glomerular Diseases.

Vascular Diseases.

Interstitial Disease.

Tubular Diseases.

Chapter 10.

Acute Renal Failure in the Transplanted Kidney.

Kim Solez and Lorraine C Racusen.

Acute Rejection.

Acute Tubule Necrosis.

Cyclosporine Toxicity.

Posttransplant Lymphoprolifertive Disorder.

Subclinical Rejection.

Thrombotic Microangiopathy.

Chapter 11.

Renal Injury Due to Environmental Toxins, Drugs and Contrast Agents.

Marc E De Broe.

General Nephrotoxic Factors.

Aminoglycosides.

Amphotericin B.

Cyclosporine.

Lithium-Induced Acute Renal Faliure.

Inhibitors of the Renin-Angiotensin System.

Nonsteroidal Anti-inflammatory Drugs.

Contrast Medium-Associated Nephrotoxicity.

Chapter 12.

Diagnostic Evaluation of the Patient with Acute Renal Faliure.

Brian G Dwinnell and Robert J Anderson.

Blood Urea Nitrogen, Creatinine, and Renal Failure.

Categorization of Causes of Acute Renal Failure.

Diagnostic Steps in Evaluating Acute Renal Failure.

Vascular Mechanisms Involved in Acute Renal Failure.

Acute Glomerulonephritis.

Interstitial Nephritis.

Acute Tubular Necrosis.

Nephrotoxin Acute Renal Failure.

Chapter 13.

Pathophysiology of Ischemic Acute Renal Failure: Cytoskeletal Aspects Bruce A Molitoris and Robert Bacallao.

Chapter 14.

Pathophysiology of Ischemic Acute Renal Failure.

Michael S Goligorsky and Wilfred Lieberthal.

Vasoactive Hormones.

Leukocytes in Acute Renal Failure.

Mechanisms of Cell Death: Necrosis and Apoptosis.

Chapter 15.

Pathophysiology of Nephrotoxic Acute Renal Failure.

Rick G Schnellmann and Katrina J Kelly.

Clinical Significance of Toxincant-Medicated Acute Renal Failure.

Renal Cellular Responses to Toxicant Exposures.

Mechanisms of Toxicant-Medicated Cellular Injury.

Chapter 16.

Acute Renal Failure: Cellular Features of Injury and Repair Kevin T Bush, Hiroyuki Sakurai, Tatsuo Tsukamoto, and Sanjay K Nigam.

The Ischemic Epithelial Cell.

Reassembly of the permeability Barrier.

The Endoplasmic Reticulum Stress Response in Ischemia.

Growth Factors and Morphogenesis.

Chapter 17.

Molecular Responses and Growth Factors.

Steven B Miller and Babu J Padanilam.

Growth Factors in Acute Renal Failure.

Clinical use of Growth Factors in Acute Renal Failure.

Future Directions.

Chapter 18.

Nutrition and Metabolism in Acute Renal Failure.

Wilfred Druml.

Metabolic Alterations in Acute Renal Failure.

Metabolic Impact of Renal Replacement Therapy.

Nutrition, Renal Function, and Recovery.

Desision Making, Patient Classification, and Nutritional Requirements.

Enteral Nutrition.

Parenteral Nutrition.

Volume 2.

Section I: Glomerulonephritis and Vasculitis.

Introduction: Richard J Glassock and Arthur H Cohen.

Chapter 1.

Normal Vascular and Gomerular Anatomy.

Arthur H Cohen and Richard J Glassock.

Chapter 2.

The Primary Glomerulopathies.

Arthur H Cohen and Richard J Glassock.

Minimal Change Disease.

Focal Segmental Glomerulosclerosis.

Membranous Glomerulonephritis.

Membranoproliferative Glomerulonephritis.

Mesangial Proliferative Glomerulonephritis.

Crescentic Glomerulonephritis.

Immunoglobulin A Nephropathy.

Fibrillary and Immunotactoid.

Glomerulonephritis.

Collagenofibrotic Glomerulopathy.

Chapter 3.

Heredofamilial and Congenital Glomerular Disorders.

Arther H Cohen and Richard J Glassock.

Chapter 4.

Infection-Associated Glomerulopathies.

Arther H Cohen and Richard J Glassock.

Chapter 5.

Vascular Disorders.

Arther H Cohen and Richard J Glassock.

Section II: Tubulointerstitial Disease.

Introduction: Jean Pierre Grunfeld.

Chapter 6.

Renal Interstitium and Major Features of Chronic Tubulointerstitial Nephritis Garabed Eknoyan and Luan D Truong.

Stucture of the Interstitium.

Function of the Interstitium.

Pathologic Features of Chronic TIN.

Pathogenesis of Chronic TIN.

Patterns of Tubular Dysfunction.

Correlates of Tubular Dysfunction with Severity of Chronic TIN.

Correlates of Chronic TIN with Progressive Renal Failure.

Drugs.

Heavy Metals.

Ischemic Vascular Disease.

Obstruction.

Hematopoietic Diseases.

Hematologic Diseases.

Metabolic Disorders.

Granulomatous Diseases.

Endemic Diseases.

Hereditary Diseases.

Papillary Necrosis.

Chapter 7.

Unrinary Tract Infection.

Alain Meyrier.

Diagnosis.

Bacteriology.

Virulence Factors of Uropathogenic Strains.

Classification of Urinary Tract Infection.

Imaging.

Special Forms of Renal Infection.

Chapter 8.

Reflux and Obstructive Nephropathy.

James M Gloor and Vicente E Torres.

Anatomy of Vericoureteric Reflux.

Pathogenesis of Vesicoureteric Reflux and Reflux Nephropathy.

Diagnosis of Vesicoureteric Reflux and Reflux Nephropathy.

Clinical Course of Vesicoureteric Reflux.

Treatment of Vesicoureteric Reflux.

Complications of Reflux Nephropathy.

Pathogenesis of Obstructive Nephropathy.

Clinical Manifestations of Obstructive Nephropathy.

Diagnosis of Obstructive Nephropathy.

Posterior Urethral Valves.

Ureterovesical Junction Obstruction.

Retroperitoneal Fibrosis.

Chapter 9.

Cystic diseases of The Kidney.

Yves Pirson and Dominique Chauveau.

General Features.

Nongenetic Disorders.

Genetic Disorders.

Chapter 10.

Toxic Nephropathies.

Jean-Louis Vanherweghem.

Exposure to Nephrotoxins.

Exposure to Metals.

Exposure to Analgesics.

Exposure to Cyclosporine.

Exposure to Aminosalicylic Acid.

Exposure to Ochratoxins.

Exposure to Chinese Herbs.

Chapter 11.

Metabolic Causes of Fubulointerstitial Disease.

Steven J Scheinman.

Chapter 12.

Renal Tubular Disorders.

Lisa M Guay-Woodford.

Overview of Renal Tubular Disorders.

Renal Glucosuria.

Aminoacidurias.

Renal Hypophosphatemic Rickets.

Fanconi's Syndrome.

Renal Tubular Acidoses.

Bartter-like Syndromes.

Pseudogypoparathyroidism.

Disorders of Aldosterone-Regulated Transport.

Nephrogenic Diabetes Insipidus.

Urolithiases.

Index.

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Volume 3.

The kidney in blood pressure regulation;.

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Renal parenchymal disease and hypertension;.

Renovascular hypertension and ischemic nephropathy;.

Adrenal causes of hypertension;.

Insulin resistance and hypertension;.

The role of hypertension in progression of chronic renal disease;.

Pharmacologic treatment of hypertension;.

Hypertensive crises.

Index.

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Volume 4.

Diabetic nephropathy: impact of comorbidity;.

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Vasculitis (polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, Henoch-Schonlein purpura);.

Amyloidosis; Sickle cell disease;.

Renal involvement in malignancy;.

Renal involvement in tropical diseases;.

Renal disease in patients infected with hepatitis and human immunodeficiency virus;.

Renal involvement in sarcoidosis;.

Renal involvement in essential mixed cryoglobulinemia;.

Kidney disease and hypertension in pregnancy;.

Renal involvement in collagen vascular diseases and dysproteinemias.

Index.

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Volume 5.

Section I: Dialysis as Treatment of End-Stage Renal Disease - Principles of dialysis: diffusion, convection, and dialysis machines;.

Dialysate composition in hemodialysis and peritoneal dialysis;.

High-efficiency and high-flux hemodialysis;.

Principles of peritoneal dialysis;.

Dialysis access and recirculation;.

The dialysis prescription and urea modeling;.

Complications of dialysis: selected topics.

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Section II: Transplantation as Treatment of End-Stage Renal Disease - Histocompatibility testing and organ sharing;.

Transplant rejection and its treatment;.

Post-transplant infections;.

Immunosuppressive therapy and protocols;.

Evaluation of prospective donors and recipients;.

Medical complications of renal transplantation;.

Technical aspects of renal transplantation;.

Kidney-pancreas transplantation;.

Transplantation in children;.

Recurrent disease in the transplanted kidney.

Index.