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- Wiley
More About This Title Biopharmaceuticals - Biochemistry andBiotechnology 2e
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This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.
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Gary Walsh is a senior lecturer in industrial biochemistry at the University of Limerick, Ireland. He combines industrial experience within the pharmaceutical industry with an extensive teaching and academic research background in pharmaceutical biotechnology. He has published half a dozen highly acclaimed books on various aspects of protein biotechnology. He is on the editorial board of several biopharmaceutical journals and is closely affiliated with the European Association of Pharma Biotechnology, serving as its scientific secretary.
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Chapter 1. Pharmaceuticals, biologies and biopharmaceuticals.
Chapter 2. The drug development process.
Chapter 3. The drug manufacturing process.
Chapter 4. The cytokines—the interferon family.
Chapter 5. Cytokines: interleukins and tumour necrosis factor.
Chapter 6. Haemopoietic growth factors.
Chapter 7. Growth factors.
Chapter 8. Hormones of therapeutic interest.
Chapter 9. Blood products and therapeutic enzymes.
Chapter 10. Antibodies, vaccines and adjuvants.
Chapter 11. Nucleic acid therapeutics.
Appendix 1. Biopharmaceuticals thus far approved in the USA or European Union.
Appendix 2. Some Internet addresses relevant to the biopharmaceutical sector.
Appendix 3. Two selected monographs reproduced from the European Pharmacopoeia with permission from the European Commission: I. Products of recombinant DNA Technology; II. Interferon a -2 concentrated solution.
Appendix 4. Manufacture of biological medicinal products for human use. (Annex 2 from The Rules Governing Medicinal Products in the European Community, Vol. 4, Good Manufacturing Practices for Medicinal Products).
Index.
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"...well written… (and) copiously illustrated..." (Chemistry & Industry, 17th January 2005)
“This book should be recommended reading for all under-graduate course in pharmacy and the pharmaceutical sciences …”. (Cell Biochemistry & Function, March-April 2005)